After Harrison Wells, Cisco Ramon and Barry Allen arrived on Earth Two, they were politely greeted by Henry, which caused Cisco and Barry to freak out due to his counterpart being a super villain back on their Earth. When Zoom attacked S.T.A.R. Labs, he interrogated Henry to learn Harrison Wells' location. His fate is unknown.
Unlike his Earth One counterpart who is a hot-headed, temperamental and egotistical meta-human, Henry is a kind-hearted, polite and friendly lab assistant who seems to have a very good relationship with his boss Harrison Wells.