Guardian's team operates in National City of Earth Thirty-Eight. Guardian's team protects National City from anyone who means to cause it harm. James Olsen/Guardian is the leader of this team, which consists of Winn Schott and Lyra Strayd. Guardian's team also works with the D.E.O. and Supergirl's team, which are the team's biggest allies.
James's camera gets destroyed by criminals who obtained alien weaponry supplied by Cadmus. Winn tries if he stays out of being a crime fighter until it is ready.
- James Olsen/Guardian (founder, leader, acting CEO of CatCo Worldwide Media, photographer and field support)
- Winn Schott/Man in the Van (D.E.O. agent, computer hacker and tech support)
- Lyra Strayd (field support)
- Supergirl's team
- Lena Luthor
- Olivia Marsdin
- Cat Grant
- Kal-El/Clark Kent/Superman
- Mon-El/Mike Matthews (forced to leave under difficult circumstances)