- "Poor, sweet boy actually wanted to scrap the whole thing just because of a pesky little side effect that removes free will. Not financially responsible. Luckily, I was there to step in. You know it's true what they say? Behind every great man is a strong woman."
- —Beth Breen to Lena Luthor[src]
Beth Breen is the corrupt former CFO of Spheerical Industries. She was arrested for two accounts of murder and conspiracy for using the Biomax technology to control the late Jack Spheer against his will.
Beth worked with Jack Spheer as the Chief Financial Officer of his company. When Jack tried to perfect the Biomax nanobots, he tested the nanotechnology on himself and realized there was a dangerous side effect in which the nanobots took over the subject's mind. He wanted to shut down the program but Beth knew that scrapping the project would be a huge financial loss for the company. Jack's body had fused with the Biomax so Bree used the tech to control him through a neurotransmitter, making him the perfect figurehead. Bree also arranged for falsified human test trials, payoffs for the selected candidates, and for lab technician Joe Watkins to be fired when he realized that the Biomax hadn't actually been tested. Beth and Jack claimed that the Biomax nanobots were now perfected and ready for distribution.
Beth and Jack went to National City to launch their campaign with a press-filled presentation. However, Beth realized there were leaks within the company that tried to go to both Kara Danvers and Snapper Carr to expose the truth about Biomax, including Joe and one of the "test subjects", Derrick Simmons. She controlled Jack and had him kill the two before they divulged the truth to Kara and Snapper, respectively. Afterwards, Kara had gone to Lena Luthor about what was happening and the latter went to confront Jack at a Spheerical Industries lab. However, when Lena saw that Jack didn't know what she was talking about, Beth revealed herself as the real culprit and that Jack was simply was an unwilling tool. Beth explained that Jack's decision wasn't financially responsible and she had to had to step in to save the company. Lena believed Beth was going to kill her but Beth pointed out that killing Lena also wasn't financially responsible. Instead, if she controlled Lena as well, she would gain access to L-Corp to further the Biomax program. Beth tried to have Jack inject the nanobots into Lena, but Supergirl showed up and saved her. Beth commanded Jack to attack Supergirl with the Biomax swarm. When confronted by Lena, Beth kicked her in the mid-section and boasted at having achieved a black belt degree. However, Lena quickly recovered and knocked Beth out with a couple punches. As Lena moved to override the Biomax, Beth warned her that the nanobots had merged with Jack and disabling it would kill him, but was promptly knocked out again. Lena disabled the Biomax at Jack's urging, killing him.
Beth was an immoral, selfish, ruthless individual. She wanted to freely market dangerous nanotechnology for the sake of fame and money without regard for the potential consequences on its subjects. Beth will not hesitate to kill those who oppose her or use them to her advantage: She turned Jack Spheer into her figurehead when he wanted to discontinue the Biomax project and callously used him to murder two people who tried to bring the truth about the project to light. However, Beth is also pragmatic and always thinks ahead; when Lena Luthor discovered her plan, Beth tried to take over her mind as well to get access to L-Corp's resources for the Biomax project instead of simply killing her.
Beth was shown to be prideful and arrogant as well, believing she was "a realist" and felt justified in her actions to ensure a prosperous future for Spheerical Industries. Even on the verge of defeat, Beth showed no remorse for her crimes and even sadistically gloated to Lena that overriding the Biomax program would kill Jack.
- High-level Intellect/Business Acumen/Skilled Tactician: As a businesswoman, Beth knew how to market products to ensure they reach the masses and was in charge of overseeing Spheerical Industries's financial affairs. Beth had considerable knowledge on the Biomax technology, using a neurotransmitter to control Jack Spheer and weaponize the nanobots that merged with him. Beth intended to pin her crimes on Jack if anyone caught onto her plan, and would have succeeded if Supergirl and Lena Luthor hadn't defeated her.
- Skilled combatant: Beth is a black belt which makes her a capable fighter. However, she was taken down rather quickly by Lena in single combat. This is most likely because Lena was able to catch her off guard.